Main Street Paws
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Independent Vets & Veterinarians in Johns Island, SC

Every clinic below is screened against corporate chain and consolidator lists — and the ones with a Verified badge have confirmed their independent ownership with us.

Help us keep this directory accurate. We verify independence continuously — if you don’t see your favorite clinic, suggest it below; if a listing is closed or has been purchased by a corporate group, use Report on its card. That’s how this stays a directory of truly independent businesses.

Lowcountry Veterinary Neurology & Surgery

Specialty care · Mount Pleasant, SC

(843) 273-6116582 Lone Tree DriveClaim this listingReport

Vetco Vaccination Clinic

General practice · North Charleston, SC

(843) 764-28757400 Rivers AvenueClaim this listingReport

Cats Only Animal Hospital

General practice · Mount Pleasant, SC

(843) 849-16611492 North Highway 17Claim this listingReport

Veterinary Dental Care

General practice · Mount Pleasant, SC

(843) 964-74741510 Mathis Ferry RoadClaim this listingReport

Vetco Vaccination Clinic

General practice · Mount Pleasant, SC

(843) 388-28431501 North Highway 17Claim this listingReport

Best Friends Animal Clinic

General practice · Hanahan, SC

(843) 414-7455Tanner Hall BoulevardClaim this listingReport

Lowcountry Pet Wellness Clinic

General practice · North Charleston, SC

(843) 556-7387Eagle Landing BoulevardClaim this listingReport

Long Point Animal Hospital

General practice · Mount Pleasant, SC

(843) 971-7701757 Long Point RoadClaim this listingReport

Sweetgrass Animal Hospital

General practice · Summerville, SC

(843) 225-96639730 Dorchester RoadClaim this listingReport

Clements Ferry Veterinary

General practice · Charleston, SC

(843) 471-17112020 Wambaw Creek RoadClaim this listingReport

Shuler Veterinary Clinic

General practice · Mount Pleasant, SC

(843) 428-61711769 North Highway 17Claim this listingReport

Merrill P Irvin DVM

General practice · North Charleston, SC

(843) 553-04418320 Rivers AvenueClaim this listingReport

Northwoods Veterinary Clinic

General practice · North Charleston, SC

(843) 553-0441Goose Creek Boulevard NorthClaim this listingReport

Ford Molly L DVM

General practice · North Charleston, SC

(843) 553-04418320 Rivers AvenueClaim this listingReport

Jagocki Tracy DVM

General practice · North Charleston, SC

(843) 553-04418320 Rivers AvenueClaim this listingReport

Summerville Pet Clinic

General practice · Summerville, SC

(843) 718-89801810 Old Trolley RoadClaim this listingReport

Oakbrook Veterinary Clinic

General practice · Summerville, SC

(843) 871-29001705 Old Trolley RoadClaim this listingReport

Tidewater Veterinary

General practice · Mount Pleasant, SC

(843) 856-73001964 Riviera DriveClaim this listingReport

Coastal Creek Animal Hospital

General practice · Summerville, SC

(843) 948-09991203 Old Trolley RoadClaim this listingReport

Sandy Cove Veterinary Clinic

General practice · Isle of Palms, SC

(843) 885-69691521 Palm BoulevardClaim this listingReport

Ladson Veterinary Hospital

General practice · Ladson, SC

(843) 900-16003679 Ladson RoadClaim this listingReport

Animal Eye Care of the Lowcountry

General practice · Ladson, SC

(843) 207-49699565 Highway 78Claim this listingReport

Goose Creek Veterinary Clinic

General practice · Goose Creek, SC

Palmetto Veterinary Hospital

General practice · Mount Pleasant, SC

(843) 881-99152443 North Highway 17Claim this listingReport

Cainhoy Veterinary Hospital

General practice · Charleston, SC

(843) 971-6200Hopewell DriveClaim this listingReport

Old Trolley Road Animal Clinic

General practice · Summerville, SC

(843) 871-3135429 Old Trolley RoadClaim this listingReport

College Park Road Veterinary Clinic

General practice · Ladson, SC

(843) 797-1493186 College Park RoadClaim this listingReport

Flowertown Animal Hospital

General practice · Summerville, SC

(843) 875-63031357 Bacons Bridge RoadClaim this listingReport

SPCA Spay & Neuter Clinic

General practice · Goose Creek, SC

(843) 761-5266Saint James AvenueClaim this listingReport

Mt Holly Veterinary Clinic

General practice · Goose Creek, SC

(843) 553-4700Saint James AvenueClaim this listingReport

Nemasket Veterinary Clinic

General practice · Summerville, SC

(843) 871-4560605 Miles Jamison RoadClaim this listingReport

Safe Harbor Animal Hospital

General practice · Mount Pleasant, SC

(843) 474-69871161 Muhlenbergia DriveClaim this listingReport

Crescent Care Veterinary Clinic of the lowcountry

General practice · Mount Pleasant, SC

(843) 277-90433001 Rivertowne ParkwayClaim this listingReport

Ashley Pines Animal Hospital

General practice · Summerville, SC

(843) 604-89692636 Highway 17A SouthClaim this listingReport

Pet Care Professionals

General practice · Mount Pleasant, SC

(843) 925-13263022 South Morgans Point RoadClaim this listingReport

Animal Medical Clinic of Goose Creek

General practice · Goose Creek, SC

(843) 569-3647Central AvenueClaim this listingReport

VIP Petcare Vaccination Clinic

General practice · Summerville, SC

(800) 427-7973620 Bacons Bridge RoadClaim this listingReport

Lowcountry Veterinary Surgery

Specialty care · Mount Pleasant, SC

(843) 697-48723400 Salterbeck StreetClaim this listingReport

Animal Eye Care Associates

General practice · Mount Pleasant, SC

(843) 881-22423400 Salterbeck StreetClaim this listingReport

Ear Crops Home

General practice · Goose Creek, SC

(843) 824-8044431 Saint James AvenueClaim this listingReport

Creekside Veterinary Clinic

General practice · Goose Creek, SC

(843) 824-8044Saint James AvenueClaim this listingReport

Advanced Animal Care of Mt. Pleasant

General practice · Mount Pleasant, SC

(843) 884-98383373 South Morgans Point RoadClaim this listingReport

Leslie W Steele, DVM

General practice · Mount Pleasant, SC

(843) 884-98383373 South Morgans Point RoadClaim this listingReport

David E Steele, DVM

General practice · Mount Pleasant, SC

(843) 884-98383373 South Morgans Point RoadClaim this listingReport

Sweetspire Veterinary Clinic

General practice · Summerville, SC

(843) 419-7112113C North Magnolia StreetClaim this listingReport

Animal Dermatology Clinic

Specialty care · Summerville, SC

(854) 269-8848212 East 2nd North StreetClaim this listingReport

Liz Open Arms Veterinary

General practice · Summerville, SC

(854) 228-4751319 East 3rd North StreetClaim this listingReport

Park West Veterinary

General practice · Mount Pleasant, SC

(843) 971-7774Park Avenue BoulevardClaim this listingReport

Mount Holly Veterinary Clinic

General practice · Goose Creek, SC

Winn Troy L DVM

General practice · Goose Creek, SC

(843) 553-4700514 Saint James AvenueClaim this listingReport

Central Veterinary Hospital

General practice · Summerville, SC

(843) 851-21121215 Central AvenueClaim this listingReport

ShotVet @ PetSense

General practice · Goose Creek, SC

(407) 792-038498 Davenport StreetClaim this listingReport

VIP Petcare Vaccination Clinic

General practice · Goose Creek, SC

(800) 427-797398 Davenport StreetClaim this listingReport

Vetco Vaccination Clinic

General practice · Summerville, SC

(843) 879-51361101 North Main StreetClaim this listingReport

AcutePet Urgent Care

Emergency & urgent · Summerville, SC

(843) 648-9180143 Berkeley CircleClaim this listingReport

Graham Phillip DVM

General practice · Summerville, SC

(843) 871-05431665 North Main StreetClaim this listingReport

Sangaree Animal Hospital

General practice · Summerville, SC

(843) 871-05431665 North Main StreetClaim this listingReport

Brighton Animal Hospital

General practice · Tramway, SC

(843) 800-8582Nexton Square DriveClaim this listingReport

Dr. Stephen Green

General practice · Summerville, SC

(843) 851-7784478 West Butternut RoadClaim this listingReport

Knightsville Veterinary Clinic

General practice · Sweetbriar, SC

(843) 851-7784Tom Wesley LaneClaim this listingReport

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